Set in 1950s New York, “Insignificance” portrays a chance meeting of four icons: Joe DiMaggio (The Ballplayer), Albert Einstein (The Professor), Marilyn Monroe (The Actress), and Joseph McCarthy (The Senator). Their interactions spotlight the intricacies of fame, personal challenges, and post-war tensions.

The Ballplayer, Joe DiMaggio, struggles with marital issues and his baseball past. The Professor, engrossed in equations, contends with The Senator’s political threats. Meanwhile, The Actress navigates her public image and shares a profound moment with The Professor, all leading to a haunting vision of the Hiroshima bombing and a contemplation of life’s fragility.